Isoflurane activates human cardiac mitochondrial adenosine triphosphate-sensitive K+ channels reconstituted in lipid bilayers.

Abstract

BACKGROUND Activation of the mitochondrial adenosine triphosphate (ATP)-sensitive K+ channel (mitoK(ATP)) has been proposed as a critical step in myocardial protection by isoflurane-induced preconditioning in humans and animals. Recent evidence suggests that reactive oxygen species (ROS) may mediate isoflurane-mediated myocardial protection. In this study… (More)

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@article{Jiang2007IsofluraneAH, title={Isoflurane activates human cardiac mitochondrial adenosine triphosphate-sensitive K+ channels reconstituted in lipid bilayers.}, author={Ming Jiang and Yuri Nakae and Marko Ljubkovi{\'c} and Wai-Meng Kwok and David F. Stowe and Zeljko J Bosnjak}, journal={Anesthesia and analgesia}, year={2007}, volume={105 4}, pages={926-32, table of contents} }