Isoflavonoids and coumarins from Glycyrrhiza uralensis: antibacterial activity against oral pathogens and conversion of isoflavans into isoflavan-quinones during purification.

@article{Gafner2011IsoflavonoidsAC,
  title={Isoflavonoids and coumarins from Glycyrrhiza uralensis: antibacterial activity against oral pathogens and conversion of isoflavans into isoflavan-quinones during purification.},
  author={Stefan Gafner and Chantal Bergeron and Jacquelyn R. Villinski and Markus Godejohann and Pavel Kessler and John H. Ii Cardellina and Daneel Ferreira and Karine El Feghali and Daniel Grenier},
  journal={Journal of natural products},
  year={2011},
  volume={74 12},
  pages={
          2514-9
        }
}

• Stefan Gafner, Chantal Bergeron, +6 authors Daniel Grenier
• Published in Journal of natural products 2011
• DOI:10.1021/np2004775

Phytochemical investigation of a supercritical fluid extract of Glycyrrhiza uralensis has led to the isolation of 20 known isoflavonoids and coumarins, and glycycarpan (7), a new pterocarpan. The presence of two isoflavan-quinones, licoriquinone A (8) and licoriquinone B (9), in a fraction subjected to gel filtration on Sephadex LH-20 is due to suspected metal-catalyzed oxidative degradation of licoricidin (1) and licorisoflavan A (2). The major compounds in the extract, as well as 8, were… CONTINUE READING

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