Isoflavones: estrogenic activity, biological effect and bioavailability

  title={Isoflavones: estrogenic activity, biological effect and bioavailability},
  author={Daniela Cristina Vitale and Cateno Piazza and Barbara Melilli and Filippo Drago and Salvatore Salomone},
  journal={European Journal of Drug Metabolism and Pharmacokinetics},
Isoflavones are phytoestrogens with potent estrogenic activity; genistein, daidzein and glycitein are the most active isoflavones found in soy beans. Phytoestrogens have similarity in structure with the human female hormone 17-β-estradiol, which can bind to both alpha and beta estrogen receptors, and mimic the action of estrogens on target organs, thereby exerting many health benefits when used in some hormone-dependent diseases. Numerous clinical studies claim benefits of genistein and… CONTINUE READING
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