Isoenzyme-specific protein kinase C and c-Jun N-terminal kinase activation by electrically stimulated contraction of neonatal rat ventricular myocytes.

@article{Strait2000IsoenzymespecificPK,
  title={Isoenzyme-specific protein kinase C and c-Jun N-terminal kinase activation by electrically stimulated contraction of neonatal rat ventricular myocytes.},
  author={James B. Strait and Allen M. Samarel},
  journal={Journal of molecular and cellular cardiology},
  year={2000},
  volume={32 8},
  pages={1553-66}
}
Previous studies from our laboratory and others indicate that contraction-induced mechanical loading of cultured neonatal rat ventricular myocytes produces many of the phenotypic changes associated with cardiomyocyte hypertrophy in vivo, and that these changes occur via the activation of serine-threonine protein kinases. These may include the extracellular… CONTINUE READING