Isoelectric focusing of CSF proteins and the future evolution of multiple sclerosis: a clinical follow-up

@article{Ersmark1984IsoelectricFO,
  title={Isoelectric focusing of CSF proteins and the future evolution of multiple sclerosis: a clinical follow-up},
  author={B. Ersmark and {\AA}ke Sid{\'e}n},
  journal={Journal of Neurology},
  year={1984},
  volume={231},
  pages={117-121}
}
A clinical follow-up covering a period of 5–10 years after onset was performed in 150 patients with optic neuritis or other potential onset symptoms of MS. Thin-layer isoelectric focusing had been used for the initial CSF-protein analysis. No evidence for a more probable alternative diagnosis appeared in 147 patients while a non-MS diagnosis was established in 3 patients. Among these 147 subjects the planned follow-up was accomplished in 131 patients, but not in 16. An evolution into clinically… CONTINUE READING

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