Isocyanide-Based Multicomponent Reactions for the Synthesis of Heterocycles

Abstract

Multicomponent reactions (MCRs) are extremely popular owing to their facile execution, high atom-efficiency and the high diversity of products. MCRs can be used to access various heterocycles and highly functionalized scaffolds, and thus have been invaluable tools in total synthesis, drug discovery and bioconjugation. Traditional isocyanide-based MCRs… (More)
DOI: 10.3390/molecules21010019

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