Isochorismate synthase is required to synthesize salicylic acid for plant defence

@article{Wildermuth2001IsochorismateSI,
  title={Isochorismate synthase is required to synthesize salicylic acid for plant defence},
  author={Mary C. Wildermuth and Julia Dewdney and Gang Wu and Frederick M. Ausubel},
  journal={Nature},
  year={2001},
  volume={414},
  pages={562-565}
}
Salicylic acid (SA) mediates plant defences against pathogens, accumulating in both infected and distal leaves in response to pathogen attack. Pathogenesis-related gene expression and the synthesis of defensive compounds associated with both local and systemic acquired resistance (LAR and SAR) in plants require SA. In Arabidopsis, exogenous application of SA suffices to establish SAR, resulting in enhanced resistance to a variety of pathogens. However, despite its importance in plant defence… CONTINUE READING
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