Islet-1 cells are cardiac progenitors present during the entire lifespan: from the embryonic stage to adulthood.

@article{Genead2010Islet1CA,
  title={Islet-1 cells are cardiac progenitors present during the entire lifespan: from the embryonic stage to adulthood.},
  author={Rami Genead and Christian Danielsson and Agneta Birgitta Andersson and Matthias Corbascio and Anders Franco-Cereceda and Christer Sylven and Karl-Henrik Grinnemo},
  journal={Stem cells and development},
  year={2010},
  volume={19 10},
  pages={1601-15}
}
The aim of this study was to longitudinally characterize the distribution of cells actively expressing the progenitor transcription factor islet-1 (Isl1+) during the embryonic life, the postnatal period, and adulthood. In this study, we have used direct immunohistochemical staining toward the protein Isl1 in a longitudinal rat model. Cells actively expressing Isl1 were traced in embryos from gestational day (GD) 11 until adulthood. In early cardiac development (GD 11), the Isl1+ progenitors… CONTINUE READING

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