Island Cells Control Temporal Association Memory

  title={Island Cells Control Temporal Association Memory},
  author={Takashi Kitamura and Michele Pignatelli and Junghyup Suh and Keigo Kohara and Atsushi Yoshiki and Kuniya Abe and Susumu Tonegawa},
Episodic memory requires associations of temporally discontiguous events. In the entorhinal-hippocampal network, temporal associations are driven by a direct pathway from layer III of the medial entorhinal cortex (MECIII) to the hippocampal CA1 region. However, the identification of neural circuits that regulate this association has remained unknown. In layer II of entorhinal cortex (ECII), we report clusters of excitatory neurons called island cells, which appear in a curvilinear matrix of… CONTINUE READING
Highly Influential
This paper has highly influenced 12 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS
Recent Discussions
This paper has been referenced on Twitter 53 times over the past 90 days. VIEW TWEETS


Publications citing this paper.
Showing 1-10 of 76 extracted citations


Publications referenced by this paper.
Showing 1-10 of 27 references

Front. Synaptic Neurosci

  • L M Teles-Grilo, J R Ruivo, Mellor
  • Front. Synaptic Neurosci
  • 2013

Nat. Neurosci

  • J J Couey
  • Nat. Neurosci
  • 2013

Philos. Trans. R. Soc. London B Biol. Sci

  • M Brecht
  • Philos. Trans. R. Soc. London B Biol. Sci
  • 2013

Science Curr. Opin. Neurobiol

  • S J Zhang
  • Science Curr. Opin. Neurobiol
  • 2013

Nat. Methods

  • J Mattis
  • Nat. Methods
  • 2012


  • L M Giocomo
  • Cell
  • 2011

Front Syst Neurosci

  • X Han
  • Front Syst Neurosci
  • 2011

Proc. Natl. Acad. Sci. U.S.A

  • S E Lee
  • Proc. Natl. Acad. Sci. U.S.A
  • 2010

Neurosci. Res

  • J Kawano
  • Neurosci. Res
  • 2009

J. Neurosci

  • L M Giocomo, M E Hasselmo
  • J. Neurosci
  • 2008

Similar Papers

Loading similar papers…