Ischemic stroke in young patients with activated protein C resistance. A report of three cases belonging to three different kindreds.

@article{Simioni1995IschemicSI,
  title={Ischemic stroke in young patients with activated protein C resistance. A report of three cases belonging to three different kindreds.},
  author={Paolo Simioni and Hans de Ronde and Paolo Prandoni and Marina Saladini and Rogier M. Bertina and Antonio Girolami},
  journal={Stroke},
  year={1995},
  volume={26 5},
  pages={885-90}
}
BACKGROUND A new pathological condition termed "activated protein C (APC) resistance" has recently been reported to be the most common hereditary blood coagulation disorder associated with familial thrombosis. APC resistance is characterized by a poor anticoagulant response to APC in the plasma of patients and is due to a defect of factor V. CASE DESCRIPTIONS This report deals with three Italian families with inherited APC resistance in which stroke had occurred at a young age in one of the… CONTINUE READING

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