Ischemic pre-conditioning preserves brain mitochondrial functions during the middle cerebral artery occlusion in rat.

@article{Zhang2003IschemicPP,
  title={Ischemic pre-conditioning preserves brain mitochondrial functions during the middle cerebral artery occlusion in rat.},
  author={Hai-xia Zhang and Guanhua Du and J Zhang},
  journal={Neurological research},
  year={2003},
  volume={25 5},
  pages={471-6}
}
It is well known that a brief period of ischemia increases tolerance to a subsequent severe ischemic episode. In the present study, bilateral carotid arteries occlusion (BCAO) was applied as pre-conditioning to testify whether this kind of ischemia could preserve the function of mitochondria with the impairment induced by middle cerebral artery occlusion (MCAO) in brain. The activities of respiratory enzyme complex I to IV, mitochondria swelling, membrane potential, and membrane fluidity were… CONTINUE READING

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