Ischemic pre-conditioning enhances the mobilization and recruitment of bone marrow stem cells to protect against ischemia/reperfusion injury in the late phase.

@article{Kamota2009IschemicPE,
  title={Ischemic pre-conditioning enhances the mobilization and recruitment of bone marrow stem cells to protect against ischemia/reperfusion injury in the late phase.},
  author={Takahiro Kamota and T S Li and Noriyasu Morikage and Masanori Murakami and Mako Ohshima and Masayuki Kubo and Toshiro Kobayashi and Akihito Mikamo and Yasuhiro Ikeda and Masunori Matsuzaki and Kimikazu Hamano},
  journal={Journal of the American College of Cardiology},
  year={2009},
  volume={53 19},
  pages={1814-22}
}
OBJECTIVES The aim of this study was to investigate whether the mobilization and recruitment of bone marrow stem cells (BMSCs) contribute to cardioprotection in the late phase after ischemic pre-conditioning (IPC). BACKGROUND IPC is an innate phenomenon in which brief exposure to sublethal ischemia provides tissue protection from subsequent ischemia/reperfusion (I/R) injury. A delayed cardioprotection also occurs after IPC, but the precise mechanism is unclear. METHODS IPC was created with… CONTINUE READING