Ischemic neurons in rat brains after 6, 8, or 10 minutes of transient hypoxic ischemia.

@article{Radovsky1997IschemicNI,
  title={Ischemic neurons in rat brains after 6, 8, or 10 minutes of transient hypoxic ischemia.},
  author={Ann E Radovsky and Laurence M. Katz and Uwe Ebmeyer and Peter J Safar},
  journal={Toxicologic pathology},
  year={1997},
  volume={25 5},
  pages={500-5}
}
The incidence and distribution of ischemic (necrotic) neurons in the brains of rats 72 hr after hypoxic ischemia induced via asphyxiation is described and scored. Anesthetized Sprague-Dawley rats (10/group) were endotracheally intubated and had their airways occluded for 6, 8, or 10 min, which resulted, respectively, in approximately 3, 5, or 7 min of pulselessness (MABP < 10 mm Hg). Survival was 10/10, 9/10, and 6/10 in the 6-, 8-, and 10-min groups: deaths occurred within 1 hr after… CONTINUE READING

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