Ischemic nephropathy/azotemic renovascular disease.

  title={Ischemic nephropathy/azotemic renovascular disease.},
  author={Stephen C. Textor and Christopher Stuart Wilcox},
  journal={Seminars in nephrology},
  volume={20 5},
Atherosclerotic renal vascular disease can impair kidney perfusion and lead to deterioration of kidney function. The mechanisms by which reversible tissue injury becomes irreversible are not yet certain, although multiple pathways for activation of inflammatory cytokines and tissue fibrosis have been identified. The clinical hallmark of this disorder is loss of glomerular filtration beyond renal artery stenosis affecting the entire renal mass, usually associated with progressive hypertension… CONTINUE READING


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