Ischemic and anesthetic preconditioning reduces cytosolic [Ca2+] and improves Ca(2+) responses in intact hearts.

Abstract

Ca(+) loading during reperfusion after myocardial ischemia is linked to reduced cardiac function. Like ischemic preconditioning (IPC), a volatile anesthetic given briefly before ischemia can reduce reperfusion injury. We determined whether IPC and sevoflurane preconditioning (SPC) before ischemia equivalently improve mechanical and metabolic function… (More)

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@article{An2001IschemicAA, title={Ischemic and anesthetic preconditioning reduces cytosolic [Ca2+] and improves Ca(2+) responses in intact hearts.}, author={J. An and Sriram Varadarajan and Enis Novalija and David F. Stowe}, journal={American journal of physiology. Heart and circulatory physiology}, year={2001}, volume={281 4}, pages={H1508-23} }