Ischemia-reperfusion of small liver remnant promotes liver tumor growth and metastases--activation of cell invasion and migration pathways.

@article{Man2007IschemiareperfusionOS,
  title={Ischemia-reperfusion of small liver remnant promotes liver tumor growth and metastases--activation of cell invasion and migration pathways.},
  author={Kwan Man and Kevin Tak-Pan Ng and Chung-Mau Lo and Joanna Wen-Ying Ho and Bai Shun Sun and Chris Kin-Wai Sun and Terence Kin-Wah Lee and Ronnie Tung-ping Poon and Sheung Tat Fan},
  journal={Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society},
  year={2007},
  volume={13 12},
  pages={1669-77}
}
Elucidating the mechanism of liver tumor growth and metastasis after hepatic ischemia-reperfusion (I/R) injury of a small liver remnant will lay the foundation for the development of therapeutic strategies to target small liver remnant injury, and will reduce the likelihood of tumor recurrence after major hepatectomy or liver transplantation for liver cancer patients. In the current study, we aimed to investigate the effect of hepatic I/R injury of a small liver remnant on liver tumor… CONTINUE READING