Ischaemic preconditioning reduces myocardial calcium overload in coronary-occluded pig hearts shown by continuous in vivo assessment using microdialysis.

@article{Waldenstrm2012IschaemicPR,
  title={Ischaemic preconditioning reduces myocardial calcium overload in coronary-occluded pig hearts shown by continuous in vivo assessment using microdialysis.},
  author={Anders Waldenstr{\"o}m and Gunnar Ronquist and A M Aberg and Katarina Ahlstr{\"o}m and Philip Hauck and Pernilla Abrahamsson and G{\"o}ran Johansson and Bj{\"o}rn Biber and Michael Haney},
  journal={Clinical physiology and functional imaging},
  year={2012},
  volume={32 2},
  pages={133-8}
}
During ischaemia, ATP depletion leads to insufficient fuelling for Na(+) /K(+) ATPase, decreased electrochemical potential and increased influx of calcium ions. This study demonstrated a means to assess the effects of ischaemic preconditioning (IP) on the free intracellular Ca(2+) pool during prolonged ischaemia. In a porcine myocardial ischaemia model, microdialysis (MD) was used for sampling of metabolic and injury markers in IP and non-IP (control) groups. (45) Ca(2+) was delivered in… CONTINUE READING
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References

Publications referenced by this paper.
Showing 1-10 of 27 references

The Authors Clinical Physiology and Functional Imaging 2011

  • vivo, A. Waldenström
  • Scandinavian Society of Clinical Physiology and…
  • 2011

tective ischaemia in patients : preconditioning and postconditioning

  • R Haworth, A Biggs
  • Cardiovasc Res
  • 2009

Validity of the microdialysis technique for experimental in vivo studies of myocardial energy metabolism

  • M Kavianipour, G Wikström, G Ronquist, A. Waldenström
  • Acta Physiol Scand
  • 2003
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