Is vascular depression a distinct sub‐type of depressive disorder? A review of causal evidence

@article{Baldwin2005IsVD,
  title={Is vascular depression a distinct sub‐type of depressive disorder? A review of causal evidence},
  author={Robert C. Baldwin},
  journal={International Journal of Geriatric Psychiatry},
  year={2005},
  volume={20}
}
  • R. Baldwin
  • Published 1 January 2005
  • Psychology
  • International Journal of Geriatric Psychiatry
Vascular depression is an important conceptual and clinical concept. 
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99 Citations
Highly Influential Citations
4
Background Citations
36
Methods Citations
1
Results Citations
3

99 Citations

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    British Journal of Psychiatry
  • 2006
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References

SHOWING 1-10 OF 122 REFERENCES
Late‐Life Depression is Associated with Arterial Stiffness: A Population‐Based Study
TLDR
To determine whether arterial stiffness is associated with depression in the elderly, a large number of elderly patients with a history of depression have had arterial stiffening problems.
The prognostic significance of abnormalities seen on magnetic resonance imaging in late life depression: clinical outcome, mortality and progression to dementia at three years
Objective. To study the course of depressive symptoms over 3 years, rate of dementia and mortality in relation to baseline neuroradiological abnormalities.
A double blind, randomized clinical trial assessing the efficacy and safety of augmenting standard antidepressant therapy with nimodipine in the treatment of ‘vascular depression’
TLDR
Calcium channel blockers are expected to improve depression reduction and to prevent recurrence of depression in this patient population and this clinical trial was designed to test these hypotheses.
Relationship between depression and cerebrovascular disease: conceptual issues.
  • R. Ramasubbu
  • Psychology, Medicine
    Journal of affective disorders
  • 2000
Cerebrovascular risk factors and depression in older primary care patients: testing a vascular brain disease model of depression.
TLDR
Data did not support the notion that a small-vessel brain disease model of depression might apply to the majority of older persons with depressive symptoms and syndromes in primary-care settings.
'Vascular depression' hypothesis.
We propose that cerebrovascular disease may predispose, precipitate, or perpetuate some geriatric depressive syndromes. The "vascular depression" hypothesis is supported by the comorbidity of…
Longitudinal increase in the volume of white matter hyperintensities in late‐onset depression
TLDR
There is little evidence that a longitudinal increase in WMH burden within an individual is associated with the onset of a late‐life depression, but one finding supporting the increased neuropathology in the form of white matter hyperintensities found in patients diagnosed with a late-onset depression is found.
Depression and vascular disease: what is the relationship?
Age and depression.
Clinical presentation of the "depression-executive dysfunction syndrome" of late life.
TLDR
Depressive symptomatology, and especially psychomotor retardation and loss of interest in activities, contributed to disability in DED patients, whereas paranoia was associated with disability independently of executive dysfunction.
...
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