Is there logic in the placebo?

  title={Is there logic in the placebo?},
  author={Peter Christian G{\o}tzsche},
  journal={The Lancet},
Meaning and an Overview of the Placebo Effect
  • H. Brody
  • Medicine
  • Perspectives in biology and medicine
  • 2018
The placebo effect can be defined as a bodily change due to the symbolic effects of a treatment or treatment situation that can then be explained by the mental processes of expectancy or conditioning and their effect on specific neuro-chemical processes that bring about end-organ changes. Expand
Rethinking placebo in psychiatry: the range of placebo effects †
The role of placebo in the pharmacotherapy of depression and complementary and alternative medicine is discussed, and the ‘efficacy paradox’ (that placebo treatments can have larger effects than ‘evidence-based treatments’) is introduced. Expand
The role of medication beliefs in side effects
The claim that non-pharmacological factors like medication beliefs can influence side effect reporting is supported by research on the nocebo effect and findings from a feasibility study of interventions to modify unhelpful medication beliefs in order to reduce side effect attribution are presented. Expand
Evidence-based medicine, "placebos" and the homeopathy controversy
Homeopathic treatment has been available on the UK’s National Health Service (NHS) since 1948. In recent years the continued provision of homeopathy through the NHS has been increasingly questionedExpand
Placebos: a review of the placebo response
  • W. Thompson
  • Medicine
  • American Journal of Gastroenterology
  • 2000
Those engaged in treatment trials must recognize and manage the reality of placebos rather than attempt to eliminate or disparage them, and factors that might influence the placebo effect such as age, gender, and social circumstances need prospective study. Expand
Magnetic Resonance Imaging Studies on Acupuncture Therapy in Depression: A Systematic Review
The most consistent functional MRI (fMRI) results showed increased N-acetylaspartate/creatine (NAA/Cr) ratios, increased ALFF in the right precuneus, decreased AL FF in the inferior frontal gyrus, and increased FC of the anterior cingulate cortex. Expand
Clinical trials in allergen immunotherapy in the age group of children and adolescents: current concepts and future needs
An international group of experts in the field of AIT has thoroughly reviewed and discussed current concepts and provided an outlook on further improvement especially in the age group of children and adolescents. Expand
Placebo effects in pain.
  • L. Colloca
  • Medicine, Psychology
  • International review of neurobiology
  • 2020
Definitions and historical notes related to placebo effects and mechanisms of placebo effects in chronic pain and other neurological disorders are focused on. Expand
Towards an account of the placebo effect: a critical evaluation alongside current evidence
This paper offers a critical analysis of several accounts of the placebo effect that have been put forward. While the placebo effect is most often thought of as a control in research and as aExpand


Measuring patients' views: the optimum outcome measure.
The London Ambulance Service's new management must make an unequivocal commitment to both basic and extended training and the establishment of systematic clinical audit to build on the progress made to date. Expand
The effect of low-level laser therapy on musculoskeletal pain: A meta-analysis
It is concluded that LLLT has no effect on pain in musculoskeletal syndromes. Expand
The placebo: from specificity to the non-specific and back.
  • M. Shepherd
  • Psychology, Medicine
  • Psychological medicine
  • 1993
The actions and effects of placebos are discussed in relation to the specific/non-specific dichotomy with particular reference to both pharmacological and psychological modes of treatment. Expand
Implications of placebo theory for clinical research and practice in pain management
The importance of investigating the placebo effect in its own right is advocated in order to better understand the long-neglected psychological aspects of the therapeutic transaction. Expand