Is there a therapeutic or pharmacokinetic rationale for amphotericin B dosing in systemic Candida infections?

OBJECTIVE To review the literature regarding the dosage of amphotericin B in Candida infections. The correlation or rationale of current dosing practices is assessed in light of the literature. DATA SOURCES A MEDLINE search encompassing the years 1968-1995 was used to identify pertinent literature. Additional references were obtained from the articles… CONTINUE READING