Is there a role for neuroleptics in bipolar depression?

  title={Is there a role for neuroleptics in bipolar depression?},
  author={Victoria C Hendrick and Lori L. Altshuler and Martin P. Szuba},
  journal={The Journal of clinical psychiatry},
  volume={55 12},
BACKGROUND Lithium, carbamazepine, and valproic acid reduce relapse rates in most bipolar patients. However, some patients with bipolar illness fail to obtain antidepressant benefits from these medications, despite appropriate dosages of and duration on therapy with these drugs. METHOD Three bipolar patients were followed in an open fashion on thymoleptic and neuroleptic medications. With discontinuation of neuroleptics, each patient relapsed into depression and was then restarted on… CONTINUE READING