Is there a role for mesenchymal stem cells in autoimmune diseases?

  title={Is there a role for mesenchymal stem cells in autoimmune diseases?},
  author={A Uccelli and Gianluigi Mancardi and Sabrina Chiesa},
  volume={41 8},
Recent reports have highlighted that adult stem cells are granted with yet poorly understood properties other than multipotentiality. In particular, mesenchymal stem cells (MSCs) represent a subset of adult stromal cells that can down-regulate several functions of the immune cells. In addition, MSCs may promote survival of damaged cells and tissues through paracrine mechanisms, possibly under the guidance of environmental cues. Thus, MSCs clinical application in autoimmune diseases seems an… CONTINUE READING

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