Is there a role for gut microbiota in type 1 diabetes pathogenesis?

@article{Bibb2017IsTA,
  title={Is there a role for gut microbiota in type 1 diabetes pathogenesis?},
  author={S. Bibb{\`o} and M. Dore and G. Pes and G. Delitala and A. Delitala},
  journal={Annals of Medicine},
  year={2017},
  volume={49},
  pages={11 - 22}
}
  • S. Bibbò, M. Dore, +2 authors A. Delitala
  • Published 2017
  • Biology, Medicine
  • Annals of Medicine
  • Abstract Type 1 diabetes mellitus (T1D) is an autoimmune disease characterized by insufficient insulin production due to the destruction of insulin secreting β-cells in the Langerhans islets. A variety of factors, including chemicals, viruses, commensal bacteria and diet have been proposed to contribute to the risk of developing the disorder. In the last years, gut microbiota has been proposed as a main factor in T1D pathogenesis. Several alterations of gut microbiota composition were described… CONTINUE READING
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    References

    SHOWING 1-10 OF 124 REFERENCES
    The role of the intestinal microbiota in type 1 diabetes mellitus
    • 196
    Toward defining the autoimmune microbiome for type 1 diabetes
    • 589
    • PDF
    The role of gut microbiota in the development of type 1, type 2 diabetes mellitus and obesity
    • 111
    Innate immunity and intestinal microbiota in the development of Type 1 diabetes
    • 1,599
    • PDF
    Gut microbiota, probiotics and diabetes
    • 178
    • PDF
    Gut microbial markers are associated with diabetes onset, regulatory imbalance, and IFN-γ level in NOD Mice
    • 72
    Long term effect of gut microbiota transfer on diabetes development.
    • 104
    Alterations in Intestinal Microbiota Correlate With Susceptibility to Type 1 Diabetes
    • 131
    • PDF
    Fecal microbiota imbalance in Mexican children with type 1 diabetes
    • 138
    • PDF