Is there a role for gut microbiota in type 1 diabetes pathogenesis?

  title={Is there a role for gut microbiota in type 1 diabetes pathogenesis?},
  author={S. Bibb{\`o} and M. Dore and G. Pes and G. Delitala and A. Delitala},
  journal={Annals of Medicine},
  pages={11 - 22}
  • S. Bibbò, M. Dore, +2 authors A. Delitala
  • Published 2017
  • Biology, Medicine
  • Annals of Medicine
  • Abstract Type 1 diabetes mellitus (T1D) is an autoimmune disease characterized by insufficient insulin production due to the destruction of insulin secreting β-cells in the Langerhans islets. A variety of factors, including chemicals, viruses, commensal bacteria and diet have been proposed to contribute to the risk of developing the disorder. In the last years, gut microbiota has been proposed as a main factor in T1D pathogenesis. Several alterations of gut microbiota composition were described… CONTINUE READING
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