Is there a place for dexmedetomidine in equine anaesthesia and analgesia? A systematic review (2005–2017)

@article{GozaloMarcilla2018IsTA,
  title={Is there a place for dexmedetomidine in equine anaesthesia and analgesia? A systematic review (2005–2017)},
  author={Miguel Gozalo-Marcilla and Frank Gasthuys and Stelio Pacca Loureiro Luna and Stijn Schauvliege},
  journal={Journal of Veterinary Pharmacology and Therapeutics},
  year={2018},
  volume={41},
  pages={205–217}
}
The objective of this review was to perform a literature compilation of all the equine publications that used dexmedetomidine as the first article on this topic was published, in 2005. We also aimed to answer the question whether the use of dexmedetomidine can currently be justified. For that, we compiled information from databases, such as PubMed, Google Scholar and Web of Science and the proceedings of the last veterinary anaesthesiology meetings. Dexmedetomidine is an attractive drug to be… 
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Comparison in Sedative Effects between Dexmedetomidine and Midazolam in Dental Implantation: A Randomized Clinical Trial
TLDR
It is considered that dexmedetomidine can achieve better postoperative analgesia, surgeon satisfaction, and sedation than midazolam.
Different doses of dexmedetomidine in children with non-tracheal intubation intravenous general anesthesia
TLDR
Injecting lower doses of dexmedetomidine to children who undergo non-tracheal intubation intravenous general anesthesia is associated with improvements in hemodynamic stability and sedation, declined incidences of restlessness and pain, and better safety profiles in children.
Dexmedetomidine contributes to reduced anesthesia dosages and improves anesthetic effectiveness in the radical resection of gastric cancer
TLDR
The application of dexmedetomidine in general anesthesia for the radical resection of gastric cancer can sharply reduce the dosage of anesthetic drugs and improve the anesthetic effect to obtain better sedation and analgesic effects, demonstrating good application values.
Recovery after General Anaesthesia in Adult Horses: A Structured Summary of the Literature
TLDR
The aim of the present article was to publish the first structured review as a summary of the literature focussing on the recovery phase after general anaesthesia in horses, taking into account the scientific evidence of the individual studies.
Evaluation of the sedative and clinical effects of xylazine, detomidine, medetomidine and dexmedetomidine in miniature donkeys
  • A. Samimi
  • Medicine
    New Zealand veterinary journal
  • 2019
TLDR
Assessment of the sedative and clinical effects of I/V xylazine, detomidine, medetomidine and dexmedETomidine in miniature donkeys found that any of the studied drugs could be used for sedation in healthy miniatureDonkeys.
Plasma concentrations at two dexmedetomidine constant rate infusions in isoflurane anaesthetized horses: a clinical study.
Quality of domestic cat semen collected by urethral catheterization after the use of different alpha 2-adrenergic agonists
TLDR
Semen collection by urethral catheterization after using α2-adrenergic agonists is a recently developed technique in feline species that is considered to be quick and highly applicable to assisted reproduction programs in felids.
Clinical Randomized Comparison of Medetomidine and Xylazine for Isoflurane Balanced Anesthesia in Horses
TLDR
In horses anesthetized with isoflurane and medetomidine or Xylazine, xylazine maintained higher MAP, reduced the dobutamine consumption and recovery time, whilst overall recovery quality was unaffected.
Ischaemic preconditioning and pharmacological preconditioning with dexmedetomidine in an equine model of small intestinal ischaemia-reperfusion
TLDR
IPC and DEX exert protective effects in experimental small intestinal ischaemia in horses, and IRI further progressed in group C, but not in IPC andDEX.
Ischaemic preconditioning and pharmacological preconditioning with dexmedetomidine in an equine model of small intestinal ischaemia-reperfusion
TLDR
IPC and DEX exert protective effects in experimental small intestinal ischaemia in horses, and IRI further progressed in group C, but not in IPC andDEX.
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