Is there a link between oestrogen therapy and gallbladder disease?

  title={Is there a link between oestrogen therapy and gallbladder disease?},
  author={Radha K. Dhiman and Yogesh K. Chawla},
  journal={Expert Opinion on Drug Safety},
  pages={117 - 129}
Cholelithiasis is the most common form of benign gallbladder disease that results in major heath expenditure. Female sex hormones are causally related to cholesterol gallstone disease, which are more common in women than in men. The risk of development of cholelithiasis is further enhanced by the use of exogenous female sex hormones and by pregnancy. Oestrogens are used in oral contraceptives and in hormone replacement therapy (HRT). Oral contraceptives do not pose a greater risk for… 

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