Is there a link between TNF gene expression and cognitive deficits in depression?

@article{Bobiska2017IsTA,
  title={Is there a link between TNF gene expression and cognitive deficits in depression?},
  author={Kinga Bobińska and Elżbieta Gałecka and Janusz Szemraj and Piotr Gałecki and Monika Talarowska},
  journal={Acta biochimica Polonica},
  year={2017},
  volume={64 1},
  pages={
          65-73
        }
}
Neuroinflammation is a known factor in the pathogenesis of recurrent depressive disorders. Depression is accompanied by activated immune-inflammatory pathways including increased levels of TNFα, sTNFR1and sTNFR2.The purpose of this study was to analyse the TNF-α, TNFRSF1A and TNFRSF1B genes on both mRNA and protein levels in patients with rDD, and to investigate the relationship between TNF-α,TNFRSF1A and TNFRSF1B gene expression and cognitive performance. The study comprised 158 subjects… CONTINUE READING

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