Is there a future for genome‐editing technologies in conservation?

  title={Is there a future for genome‐editing technologies in conservation?},
  author={J. A. Johnson and Res Altwegg and Darren M. Evans and John G. Ewen and Iain J. Gordon and Nathalie Pettorelli and Joshua K Young},
  journal={Animal Conservation},
In a recent review, Pimm et al. (2015) highlight emerging technologies in protecting biodiversity. While their list is noteworthy, the authors’ exclusion of innovations in genomic research, with the exception of single-species DNA barcoding methods, was surprising given recent advances in genome-editing technology and its potential application to conservation. Taylor & Gemmell (2016) address that deficiency in a subsequent commentary identifying three avenues where emerging genomic technologies… 

Transforming ecology and conservation biology through genome editing

Emerging and future genome‐editing technologies have the potential to transform the environmental sciences by providing new noninvasive methods for monitoring threatened species or for enhancing critical adaptive traits, and a pioneering effort by the conservation community is required to apply these technologies to real‐world conservation problems.

Technoscience and Biodiversity Conservation

  • C. Boëte
  • Environmental Science
    Asian bioethics review
  • 2018
The discovery of CRISPR/Cas9 has opened new avenues in gene editing but the eventual use of this novel approach for conservation raises concerns related to the engagement of the public, the communication between scientists, and the public and the risk of a manufactured consent.

Recent advances in conservation and population genomics data analysis

Some important themes that emerged during the workshop included the need for data visualization and its importance in finding problematic data, the effects of data filtering choices on downstream population genomic analyses, the increasing availability of whole‐genome sequencing, and the new challenges it presents.

Genomic Approaches for Conservation Management in Australia under Climate Change

The current barriers to implementing conservation genomic projects and the efforts being made to overcome them are discussed, including communication between researchers and managers to improve the relevance and applicability of genomic studies.

The Peril of Gene-Targeted Conservation.

Resurrecting biodiversity: advanced assisted reproductive technologies and biobanking

The value of cryobanking before more species are lost and the potential of advanced reproductive technologies not only to halt but also to reverse biodiversity loss are discussed.

Genetic frontiers for conservation: an assessment of synthetic biology and biodiversity conservation: technical assessment

In recent years synthetic biology has emerged as a suite of techniques and technologies that enable humans to read, interpret, modify, design and manufacture DNA in order to rapidly influence the

Harnessing synthetic biology for kelp forest conservation1

The potential direct and indirect applications of synthetic biology to kelp forest conservation are discussed and where and when it may play a role in halting or reversing global kelp loss are identified.

Population Genomics for the Management of Wild Vertebrate Populations

Overall, the potential for population genomics to improve the understanding of wild populations of fish and wildlife is seen and several important examples that are paving the way for the adoption of these technologies into management are seen.



Using genomics to characterize evolutionary potential for conservation of wild populations

Some of the complexity of adaptation genetics is explored and it is argued that screening genome‐wide variation should be a sensible approach that may provide a generalized measure of evolutionary potential that accounts for the contributions of small‐effect loci and cryptic variation.

Harnessing the power of RADseq for ecological and evolutionary genomics

This Review provides a comprehensive discussion of RADseq methods to aid researchers in choosing among the many different approaches and avoiding erroneous scientific conclusions from RADseq data, a problem that has plagued other genetic marker types in the past.

Connecting genotypes, phenotypes and fitness: harnessing the power of CRISPR/Cas9 genome editing

The numerous applications of the CRISPR/Cas9 system are reviewed and a practical guide to the creation of genetic knockouts, transgenics and other related forms of gene manipulation in nonmodel organisms is provided.

Concerning RNA-guided gene drives for the alteration of wild populations

The potential for RNA-guided gene drives based on the CRISPR nuclease Cas9 to serve as a general method for spreading altered traits through wild populations over many generations is considered.

Merging DNA metabarcoding and ecological network analysis to understand and build resilient terrestrial ecosystems

Merging metabarcoding with ecological network analysis provides a revolutionary opportunity to construct some of the largest, phylogenetically structured species-interaction networks to date, providing new ways to monitor biodiversity and ecosystem functioning and build ecosystems that are more resilient to environmental change.

Emerging Technologies to Conserve Biodiversity: Further Opportunities via Genomics. Response to Pimm et al.

Making the cut.

The genome-editing method called CRISPR has matured into a molecular marvel that much of the world—not just biologists—has noticed, which is why it has been selected Science 9s 2015 Breakthrough of

The value of avian genomics to the conservation of wildlife

Mining and characterization of candidate loci in the California condor using molecular genetic and genomic techniques as well as linkage and comparative genomic mapping will eventually enable the identification of carriers of the chondrodystrophy allele, resulting in improved genetic management of this disease.

Targeted Genome Editing for Crop Improvement

In this review, the principle of genome editing tools is summarized, focusing on the CRISPR/Cas9 system and the application of these tools to plants in the service of crop engineering.