Is there a critical developmental 'window' for isolation rearing-induced changes in prepulse inhibition of the acoustic startle response?

@article{Varty1999IsTA,
  title={Is there a critical developmental 'window' for isolation rearing-induced changes in prepulse inhibition of the acoustic startle response?},
  author={Geoffrey B. Varty and David L. Braff and Mark A. Geyer},
  journal={Behavioural brain research},
  year={1999},
  volume={100 1-2},
  pages={177-83}
}
In a previous study, rats reared in isolation from weaning exhibited normal prepulse inhibition (PPI) before puberty, whilst after puberty (6-8 weeks post weaning) isolation reared rats exhibited deficits in PPI. The developmental timing of the onset of this isolation effect appears to be critical because similar isolation of adult rats has no effect on PPI. The present study examined the time and duration of the period or 'window' of isolation necessary to induce these behavioral changes. Male… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 21 extracted citations

The Impact of Social Isolation on Rat Behaviour

Malini Veronica, Malini Veronica Porkess
2016
View 5 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…