Is the use of classical diffusion-reaction theory strictly correct with immobilized enzymes?

Abstract

The mathematical principles used for describing the simultaneous diffusion and reaction processes in heterogeneous catalysis have been carried over to model similar phenomena with immobilized enzymes. Due to the restricted mobility of the substrate molecule within the enzymes' support matrix and the stereospecificity of enzymatic catalysis it is explained how kinetic data may be both diffusionally masked and rotationally masked. This latter concept is apparently novel, and we qualitatively describe how it affects the substrate mass balance.

DOI: 10.1007/BF00131904

Cite this paper

@article{Webster2004IsTU, title={Is the use of classical diffusion-reaction theory strictly correct with immobilized enzymes?}, author={Ian A. Webster}, journal={Biotechnology Letters}, year={2004}, volume={5}, pages={207-210} }