Is the solitary dark neuron a manifestation of postmortem trauma to the brain inadequately fixed by perfusion?

@article{Cammermeyer1978IsTS,
  title={Is the solitary dark neuron a manifestation of postmortem trauma to the brain inadequately fixed by perfusion?},
  author={Jan Cammermeyer},
  journal={Histochemistry},
  year={1978},
  volume={56},
  pages={97-115}
}
Dark neurons, classified as solitary because of their sparse occurrence, were discerned in the transitional zones between gray and white matter in various species of laboratory animals fixed by perfusion. These neurons, histologically indistinguishable from dark neurons in immersion fixed material, tended to develop when the saline perfusion was delayed or slow, the amount of the Bouin fixative was excessive, or the autopsy was performed shortly after the perfusion. Under these conditions, the… CONTINUE READING

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