Is the nuclear matrix the site of DNA replication in eukaryotic cells?

Abstract

Four types of experiment were carried out to test the recently proposed model of matrix-bound replication in eukaryotic cells. In experiments with pulse-labelling we found preferential association of newly replicated DNA with the matrix only when the procedure for isolation includes first high-salt treatment of isolated nuclei and then digestion with… (More)

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@article{Djondjurov1986IsTN, title={Is the nuclear matrix the site of DNA replication in eukaryotic cells?}, author={Lalio Djondjurov and Evilina Ivanova and Dmitry M. Markov and Stoyan S Bardarov and Wilhelm Sachsenmaier}, journal={Experimental cell research}, year={1986}, volume={164 1}, pages={79-96} }