Is the minimal model too minimal?

@article{Caumo1996IsTM,
  title={Is the minimal model too minimal?},
  author={Andrea Caumo and Paolo Vicini and Professor C. Cobelli},
  journal={Diabetologia},
  year={1996},
  volume={39},
  pages={997-1000}
}
The intravenous glucose tolerance test (IVGTT: standard or modified with a tolbutamide or insulin injection) interpreted with the classic minimal model of glucose disappearance [1, 2] is a powerful non-invasire tool with which to investigate glucose metabolism in physiopathology studies. The model provides two metabolic indices measuring glucose effectiveness, Sc~ and insulin sensitivity, SI, in a single individual. S c and S I are composite parameters, i.e. they measure the net effect of… CONTINUE READING

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References

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A comparison between the minimal model and the glucose clamp in the assessment of insulin sensitivity across the spectrum of glucose tolerance

  • MF Saad, RL Anderson, al. Laws A e t
  • IRAS
  • 1994
Highly Influential
6 Excerpts

A model of glucose kinetics and their control by insulin, compartmental and noncompartmental approaches

  • C Cobelli, G Toffolo, E Ferrannini
  • Math Biosci
  • 1984
1 Excerpt

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