Is the measurement of anti-Müllerian hormone essential?

@article{Usta2012IsTM,
  title={Is the measurement of anti-M{\"u}llerian hormone essential?},
  author={Taner Usta and Engin Oral},
  journal={Current Opinion in Obstetrics and Gynecology},
  year={2012},
  volume={24},
  pages={151–157}
}
  • T. Usta, E. Oral
  • Published 1 June 2012
  • Medicine
  • Current Opinion in Obstetrics and Gynecology
Purpose of review Over the past decade, a large number of studies examining the multiple roles of anti-Müllerian hormone (AMH) have been published. The purpose of this article is to focus on the clinical usefulness of AMH in the fields of current gynecological clinical practice. Recent findings AMH has entered clinical practice in terms of poor ovarian response definition. It prevents folliculogenesis by reducing follicle sensitivity to follicle-stimulating hormone (FSH), and leads to… Expand
Predicting fertility with antimüllerian hormone: is a cutoff value adequate?
TLDR
The findings demonstrate that a TTP approach identified optimal fertility within a range of AMH values and not simply levels above a single cutoff value, which may have clinical implications for the resulting pregnancy as well. Expand
The role of anti-mullerian hormone as an indicator of reproductive health in women with obesity and concomitant polycystic ovary syndrome
Background Obesity has harmful effects on the female reproductive system. Anti-Mullerian hormone (AMH) is considered to reflect the extent of follicular growth and the reservoir of ovarian function.Expand
Anti-Müllerian Hormone Predictive Levels to Determine The Likelihood of Ovarian Hyper-Response in Infertile Women with Polycystic Ovarian Morphology
TLDR
Individualized stimulation protocols for patients with isolated PCOM and AMH greater than 4.95 ng/ml may significantly reduce the chances of developing OHSS, however, the AMH cut-off values to predict ovarian hyper- response differ for different BMI categories among PCOM patients; thus, it becomes a more precise predictive marker with increasing BMI. Expand
Anti-mullerian hormone as a predictor of ovarian reserve and ovarian response in IVF women from Gaza strip
TLDR
Anti-mullerian hormone can be used in IVF programs as a good predictor of ovarian reserve and ovarian response in response to menotrophin stimulation in in vitro fertilization (IVF) women from Gaza Strip. Expand
ANTI-MULLERIAN HORMONE AS A PREDICTOR OF OVARIAN RESERVE AND OVARIAN RESPONSE IN IVF WOMEN FROM GAZA STRIP
TLDR
Anti-mullerian hormone can be used in IVF programs as a good predictor of ovarian reserve and ovarian response in response to menotrophin stimulation in in vitro fertilization (IVF) women from Gaza Strip. Expand
Endocrine markers of ovarian function: Clinical and biological aspects with focus on Anti Müllerian hormone
TLDR
Whether there is a variation over time in secretion of AMH, and to study its relation to the two gonadotropins; FSH and LH, was explored. Expand
Elevated LH levels draw a stronger distinction than AMH in premature ovarian insufficiency
TLDR
It is concluded that the serum LH level is the most useful marker for differentiating POI cases from women with elevated FSH levels, interestingly excluding the serum AMH level in this context. Expand
Is there any correlation between amh and obesity in premenopausal women?
TLDR
Body mass index does not have an effect on serum AMH levels in women of reproductive age and Obesity has no association with levels of serum follicle stimulating hormone, luteinizing hormone, estradiol, prolactin and thyroid stimulating hormone. Expand
Bariatric Surgery Reduces Serum Anti-mullerian Hormone Levels in Obese Women With and Without Polycystic Ovarian Syndrome.
TLDR
AMH levels are elevated in PCOS patients regardless of the body weight and Bariatric surgery is effective in the normalization of AMH levels (a possible indirect marker of better fertility) only in obese patients with PCOS. Expand
Ethnic and Sociocultural Differences in Ovarian Reserve: Age-Specific Anti-Müllerian Hormone Values and Antral Follicle Count for Women of the Arabian Peninsula
TLDR
This is to-date the largest data set on age-specific AMH and AFC values in women from the Arabian Peninsula aiming to increase clinical awareness of the ovarian reserve in this population. Expand
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TLDR
AMH seems to be a better marker in predicting ovarian response to controlled ovarian stimulation than age of the patient, FSH, estradiol and inhibin B, and a similar performance for AMH and antral follicular count has been reported. Expand
The role of anti-Müllerian hormone assessment in assisted reproductive technology outcome
TLDR
AMH is able to predict extremes in ovarian response to controlled ovarian hyperstimulation but cannot predict pregnancy after ART treatment, although its future clinical role may be in the individualization of ART stimulation protocols. Expand
Anti-Mullerian hormone (AMH): what do we still need to know?
TLDR
AMH levels appear to represent the quantity of the ovarian follicle pool and may become a useful marker of ovarian reserve and in patients with premature ovarian failure AMH is undetectable or greatly reduced depending of the number of antral follicles in the ovaries. Expand
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  • Biology, Medicine
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  • 2010
TLDR
The rapid and widespread adoption of AMH assay into clinical practice demonstrates the degree of interest in this new marker amongst reproductive endocrinologists. Expand
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TLDR
Levels of anti-Mullerian hormone are highly predictive of reduced ovarian reserve and should be confirmed by a second line antral follicle count, which is suitable for screening. Expand
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TLDR
The evidence basis for using AMH for various indications is evaluated to decide how justified it is to promote AMH as a crystal ball, until more evidence is available. Expand
Anti-Mullerian hormone, inhibin B, and antral follicle count in young women with ovarian failure.
TLDR
Compared with inhibin B and AFC, AMH was more consistently correlated with the clinical degree of follicle pool depletion in young women presenting with elevated FSH levels, and may provide a more accurate assessment of the follicles pool in young hypergonadotropic patients. Expand
Anti-Müllerian hormone levels in the spontaneous menstrual cycle do not show substantial fluctuation.
TLDR
AMH levels measured through a full menstrual cycle did not show consistent fluctuation patterns in contrast to levels of FSH, LH, and estradiol, but random fluctuations were small, indicating that AMH can be relied on as a cycle-independent marker for ovarian reserve. Expand
Circulating basal anti-Müllerian hormone levels as predictor of ovarian response in women undergoing ovarian stimulation for in vitro fertilization.
TLDR
Circulating AMH has the ability to predict excessive and poor response to stimulation with exogenous gonadotrophins, and has the potential to be incorporated in to work-up protocols to predict patient's ovarian response to treatment and to individualize strategies aiming at reducing the cancellation rate and the iatrogenic complications of COH. Expand
Random anti-Müllerian hormone (AMH) is a predictor of ovarian response in women with elevated baseline early follicular follicle-stimulating hormone levels.
TLDR
A random serum AMH level is useful in setting expectations for ART prognosis in women with elevated early follicular-phase serum FSH levels, as indicated by the number of oocytes retrieved during an ART cycle. Expand
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