Is the measurement of anti-Müllerian hormone essential?

@article{Usta2012IsTM,
  title={Is the measurement of anti-M{\"u}llerian hormone essential?},
  author={Taner Usta and Engin Oral},
  journal={Current Opinion in Obstetrics and Gynecology},
  year={2012},
  volume={24},
  pages={151–157}
}
  • T. Usta, E. Oral
  • Published 1 June 2012
  • Medicine, Biology
  • Current Opinion in Obstetrics and Gynecology
Purpose of review Over the past decade, a large number of studies examining the multiple roles of anti-Müllerian hormone (AMH) have been published. The purpose of this article is to focus on the clinical usefulness of AMH in the fields of current gynecological clinical practice. Recent findings AMH has entered clinical practice in terms of poor ovarian response definition. It prevents folliculogenesis by reducing follicle sensitivity to follicle-stimulating hormone (FSH), and leads to… 

Predicting fertility with antimüllerian hormone: is a cutoff value adequate?

Anti-Mullerian hormone: reality check.

There is no current standard for AMH measurement although the UK NEQAS has been conducting an international pilot scheme for the past 2 years and it is concerning that the target levels in samples distributed to participating labs are established not against a known standard, but by using an all laboratory trimmed mean (ALTM).

The role of anti-mullerian hormone as an indicator of reproductive health in women with obesity and concomitant polycystic ovary syndrome

The level of AMH was positively correlated with both BMI and AFC, and these results reflect that body weight can play a role in the pathogenesis of polycystic ovary.

Anti-Müllerian Hormone Predictive Levels to Determine The Likelihood of Ovarian Hyper-Response in Infertile Women with Polycystic Ovarian Morphology

Individualized stimulation protocols for patients with isolated PCOM and AMH greater than 4.95 ng/ml may significantly reduce the chances of developing OHSS, however, the AMH cut-off values to predict ovarian hyper- response differ for different BMI categories among PCOM patients; thus, it becomes a more precise predictive marker with increasing BMI.

Anti-mullerian hormone as a predictor of ovarian reserve and ovarian response in IVF women from Gaza strip

Anti-mullerian hormone can be used in IVF programs as a good predictor of ovarian reserve and ovarian response in response to menotrophin stimulation in in vitro fertilization (IVF) women from Gaza Strip.

ANTI-MULLERIAN HORMONE AS A PREDICTOR OF OVARIAN RESERVE AND OVARIAN RESPONSE IN IVF WOMEN FROM GAZA STRIP

Anti-mullerian hormone can be used in IVF programs as a good predictor of ovarian reserve and ovarian response in response to menotrophin stimulation in in vitro fertilization (IVF) women from Gaza Strip.

Endocrine markers of ovarian function: Clinical and biological aspects with focus on Anti Müllerian hormone

Whether there is a variation over time in secretion of AMH, and to study its relation to the two gonadotropins; FSH and LH, was explored.

Elevated LH levels draw a stronger distinction than AMH in premature ovarian insufficiency

It is concluded that the serum LH level is the most useful marker for differentiating POI cases from women with elevated FSH levels, interestingly excluding the serum AMH level in this context.

Is there any correlation between amh and obesity in premenopausal women?

Body mass index does not have an effect on serum AMH levels in women of reproductive age and Obesity has no association with levels of serum follicle stimulating hormone, luteinizing hormone, estradiol, prolactin and thyroid stimulating hormone.

Anti-Mullerian Hormone Levels Increase After Bariatric Surgery in Obese Female Patients With and Without Polycystic Ovary Syndrome.

It is suggested that the significantly increased AMH levels by losing weight with bariatric surgery in patients with morbid obesity with and without polycystic ovary syndrome may indicate the improvement of fertilization potential.

References

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Anti-Mullerian hormone (AMH): what do we still need to know?

AMH levels appear to represent the quantity of the ovarian follicle pool and may become a useful marker of ovarian reserve and in patients with premature ovarian failure AMH is undetectable or greatly reduced depending of the number of antral follicles in the ovaries.

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  • Biology, Medicine
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  • 2010
The rapid and widespread adoption of AMH assay into clinical practice demonstrates the degree of interest in this new marker amongst reproductive endocrinologists.

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Levels of anti-Mullerian hormone are highly predictive of reduced ovarian reserve and should be confirmed by a second line antral follicle count, which is suitable for screening.

Anti-Mullerian hormone--is it a crystal ball for predicting ovarian ageing?

The evidence basis for using AMH for various indications is evaluated to decide how justified it is to promote AMH as a crystal ball, until more evidence is available.

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The basal serum AMH level could be utilized effectively to predict ovarian hyperstimulation syndrome (OHSS) and thus to direct the selection of mild COS protocols.

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Pretreatment circulating AMH level seems to be a good predictor of the ovarian response to LOD.
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