Is the flavin-deficient red blood cell common in Maremma, Italy, an important defense against malaria in this area?

@article{Anderson1994IsTF,
  title={Is the flavin-deficient red blood cell common in Maremma, Italy, an important defense against malaria in this area?},
  author={Beth Battle Anderson and Maria Luisa Scattoni and George M. Perry and Paola Galvan and M. Giuberti and Guiseppe Buonocore and Calogero Vullo},
  journal={American journal of human genetics},
  year={1994},
  volume={55 5},
  pages={
          975-80
        }
}
There is a high prevalence of a familial flavin-deficient red blood cell in Ferrara province in the Po delta in northern Italy, believed to have been selected for by malaria which was endemic from the 12th century. In the present study, activities of FAD-dependent red-cell glutathione reductase (EGR) in the Grosseto area of Maremma on the west coast of Italy where malaria was endemic from 300 B.C. are compared both with activities in the Ferrara area and with activities where there was no… CONTINUE READING