Is taxane/platinum/5 fluorouracil superior to taxane/platinum alone and does docetaxel trump paclitaxel in induction therapy for locally advanced oral cavity cancers?

@article{Noronha2015IsTF,
  title={Is taxane/platinum/5 fluorouracil superior to taxane/platinum alone and does docetaxel trump paclitaxel in induction therapy for locally advanced oral cavity cancers?},
  author={Vanita Noronha and Vijay M Patil and Amit C. Joshi and Vamshi Krishna Muddu and Atanu Bhattacharjee and Shashikant L. Juvekar and Supreeta Arya and Pankaj P. Chaturvedi and Devendra Arvind Chaukar and P. S. Sreejith Pai and Anil K. Dcruz and Kumar Prabhash},
  journal={Indian journal of cancer},
  year={2015},
  volume={52 1},
  pages={70-3}
}
BACKGROUND Cisplatin and 5 fluorouracil drug combination is inferior to the combination of taxane with these 2 drugs. However, often in clinical practice at our center giving TPF (docetaxel, cisplatin, 5 fluorouracil) is difficult in view of logistics and tolerance issues. In such a scenario, we prefer to use the 2 drugs combination of platinum and taxane. However, no study has addressed whether a 2 drugs combination, which includes taxane is inferior to the 3 drugs combination and which the… CONTINUE READING