Is sex hormone-binding globulin associated with glucose tolerance?

  title={Is sex hormone-binding globulin associated with glucose tolerance?},
  author={Aidan McElduff and Rosemary Hitchman and Patrick Mcelduff},
  journal={Diabetic medicine : a journal of the British Diabetic Association},
  volume={23 3},
BACKGROUND/AIM Women with a reduced concentration of sex hormone-binding globulin (SHBG) in the first trimester of pregnancy are at increased risk of developing gestational diabetes. Furthermore, a lower concentration of SHBG in women with gestational diabetes identifies women at increased likelihood of requiring insulin treatment. The aim of this study was to explore the relationship of SHBG concentration in pregnancy to insulin resistance and glucose tolerance. METHODS Prospective cohort… CONTINUE READING