Is serum alanine transaminase level a reliable marker of histological disease in chronic hepatitis C infection?

BACKGROUND Approximately 20-30% of patients chronically infected with hepatitis C virus (HCV) have persistently normal alanine transaminase (PNALT) levels. These patients are described to have a mild degree of histological liver damage. We aimed to assess the histological liver changes in HCV patients with PNALT. PATIENTS AND METHODS Sixty-five patients… CONTINUE READING