Is schizophrenia a progressive neurodevelopmental disorder? Toward a unitary pathogenetic mechanism.

@article{Woods1998IsSA,
  title={Is schizophrenia a progressive neurodevelopmental disorder? Toward a unitary pathogenetic mechanism.},
  author={Bryan T. Woods},
  journal={The American journal of psychiatry},
  year={1998},
  volume={155 12},
  pages={
          1661-70
        }
}
OBJECTIVE The author 1) reassesses the case against a neuronal degeneration hypothesis for schizophrenia; 2) demonstrates that the hypothesis that schizophrenia is a disorder caused by early (i.e., pre- or perinatal) and static (i.e., fixed, nonprogressive) damage to the brain is unsatisfactory because it cannot readily account for brain imaging results from schizophrenic patients and lacks both satisfactory clinical examples and experimental models of early, static developmental disorders… CONTINUE READING

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