Is running associated with a lower risk of all-cause, cardiovascular and cancer mortality, and is the more the better? A systematic review and meta-analysis

  title={Is running associated with a lower risk of all-cause, cardiovascular and cancer mortality, and is the more the better? A systematic review and meta-analysis},
  author={Željko Pedi{\vs}i{\'c} and Nipun Shrestha and Stephanie A Kovalchik and Emmanuel Stamatakis and Nucharapon Liangruenrom and Jozo Grgic and Sylvia Titze and Stuart J. H. Biddle and Adrian E Bauman and Pekka Oja},
  journal={British Journal of Sports Medicine},
  pages={898 - 905}
Objective To investigate the association of running participation and the dose of running with the risk of all-cause, cardiovascular and cancer mortality. Design Systematic review and meta-analysis. Data sources Journal articles, conference papers and doctoral theses indexed in Academic Search Ultimate, CINAHL, Health Source: Nursing/Academic Edition, MasterFILE Complete, Networked Digital Library of Theses and Dissertations, Open Access Theses and Dissertations, PsycINFO, PubMed/MEDLINE… 

Infographic. Is running associated with a lower risk of all-cause, cardiovascular and cancer mortality, and is more better? A systematic review and meta-analysis

Findings from previous studies showed inconsistent associations between running participation and all-cause, cancer and cardiovascular mortality, so a systematic review of previous studies on this topic was synthesised.

Sex-Specific Differences in Running Injuries: A Systematic Review with Meta-Analysis and Meta-Regression

Differences between female and male runners in specific injury diagnoses should be considered in the development of individualised and sex-specific prevention and rehabilitation strategies to manage running-related injuries.

Systematic Review of Psychological and Behavioral Correlates of Recreational Running

Results suggest that the identification of behavioral and psychological correlates of recreational running across populations can contribute to inform and guide a public policy agenda, focused on helping people sustain regular physical activity, through a modality they have chosen and appear to enjoy.

The association between running injuries and training parameters: A systematic review.

Despite high rates of RRIs, current evidence does not consistently link RRIs with specific training parameters or recent changes in training parameters, and caution should be taken when recommending optimal parameters or progressions.

Biosocial and disease conditions are associated with good quality of life among older adults in rural eastern Nepal: Findings from a cross-sectional study

The findings of this study reinforce the need of improving QOL of older adults through implementing programs aimed at addressing the identified biosocial and disease conditions that catalyse poor QOL in this older population residing in rural parts of Nepal.

Medical Encounters Among 94,033 Race Starters During a 16.1-km Running Event Over 3 Years in the Netherlands: SAFER XXVI.

The overall incidence of MEs was low compared with longer-distance races, but the incidence and relative frequency of serious/life-threatening MEs (44% of all MEs) was much higher and there is a need to implement prevention strategies and interventions by specialized medical practitioners in this and similar events.

Prevalence and burden of health problems in competitive adolescent distance runners: A 6-month prospective cohort study

The most burdensome health problems, irrespective of sex, included lower leg, knee, and foot/toes injuries, alongside upper respiratory illnesses, and the mean weekly prevalence of time loss was relatively low, regardless of health problem type or sex.

Omega-3 Index and AA/EPA Ratio as Biomarkers of Running-related Injuries: An Observational Study in Recreational Runners.

AbstractThe aim of this study was to examine the association between polyunsaturated fatty acids (PUFA) biomarkers, such as omega-3 (ω-3) index and arachidonic acid (AA; 20:4 ω-6)/eicosapentaenoic



Association of physical activity with all-cause and cardiovascular mortality: a systematic review and meta-analysis

Physical activity is associated with a marked decrease in cardiovascular and all-cause mortality in both men and women, even after adjusting for other relevant risk factors.

Domains of physical activity and all-cause mortality: systematic review and dose-response meta-analysis of cohort studies.

Higher levels of total and domain-specific physical activity were associated with reduced all-cause mortality and risk reduction per unit of time increase was largest for vigorous exercise.

Association of physical activity level and stroke outcomes in men and women: a meta-analysis.

Increased PA level appears beneficial in reduction of risk of stroke and related outcomes, however, higher levels of PA may be required in women to achieve as significant a risk reduction as in men.

Associations of specific types of sports and exercise with all-cause and cardiovascular-disease mortality: a cohort study of 80 306 British adults

Findings demonstrate that participation in specific sports may have significant benefits for public health, and future research should aim to further strengthen the sport-specific epidemiological evidence base and understanding of how to promote greater sports participation.

Meta-Analyses of the Effects of Habitual Running on Indices of Health in Physically Inactive Adults

Endurance running was effective in providing substantial beneficial effects on body mass, body fat, resting heart rate, VO2max, triglycerides and HDL cholesterol in physically inactive adults and the longer the length of training, the larger the achieved health benefits.

Can physical activity modulate pancreatic cancer risk? a systematic review and meta‐analysis

Despite indications of an inverse relationship with higher levels of work and total activity, there was little evidence of such associations with recreational and other activity exposures.

Long-term health benefits of physical activity – a systematic review of longitudinal studies

BackgroundThe treatment of noncommunicable diseases (NCD), like coronary heart disease or type 2 diabetes mellitus, causes rising costs for the health system. Physical activity is supposed to reduce

Physical activity and cancer: an umbrella review of the literature including 22 major anatomical sites and 770 000 cancer cases

Physical activity is associated with a lower risk of several cancers, but only colon and breast cancer associations were supported by strong or highly suggestive evidence, respectively.

Effects of frequency, intensity, duration and volume of walking interventions on CVD risk factors: a systematic review and meta-regression analysis of randomised controlled trials among inactive healthy adults

There is insufficient evidence to quantify the frequency, length, bout duration, intensity and volume of the walking required to improve CVD risk factors.