Is remodeling the dominant compensatory mechanism in both chronic heart failure with preserved and reduced left ventricular ejection fraction?

@article{MacIver2009IsRT,
  title={Is remodeling the dominant compensatory mechanism in both chronic heart failure with preserved and reduced left ventricular ejection fraction?},
  author={David Hunter MacIver},
  journal={Basic Research in Cardiology},
  year={2009},
  volume={105},
  pages={227-234}
}
The mechanisms of heart failure are ill understood with multiple, heterogeneous hypotheses proposed to describe the condition. This study examines the individual effects of left ventricular hypertrophy, long-axis shortening and the effect of left ventricular remodeling on ejection fraction, end-diastolic volume and stroke volume using a mathematical model of left ventricular contraction. Reducing long-axis shortening caused a decline in stroke volume independently of hypertrophy. Increasing… CONTINUE READING

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The model predicts that the dominant compensatory mechanism in chronic heart failure is remodeling with normalization of stroke volume .
The model predicts that the dominant compensatory mechanism in chronic heart failure is remodeling with normalization of stroke volume .
The model predicts that the dominant compensatory mechanism in chronic heart failure is remodeling with normalization of stroke volume .
The model predicts that the dominant compensatory mechanism in chronic heart failure is remodeling with normalization of stroke volume .
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