Is radioactive iodine- 131 treatment related to the occurrence of non-synchronous second primary malignancy in patients with differentiated thyroid cancer?

@article{Souza2016IsRI,
  title={Is radioactive iodine- 131 treatment related to the occurrence of non-synchronous second primary malignancy in patients with differentiated thyroid cancer?},
  author={Marcelo Cruzick de Souza and Denise Prado Momesso and Fernanda Vaisman and Leonardo Vieira Neto and Ros{\^a}ngela Aparecida Gomes Martins and Rossana Corbo and M{\'a}rio Vaisman},
  journal={Archives of endocrinology and metabolism},
  year={2016},
  volume={60 1},
  pages={9-15}
}
OBJECTIVE Much controversy relates to the risk of non-synchronous second primary malignancies (NSSPM) after radioactive iodine treatment (RAI-131) in differentiated thyroid cancer (DTC) patients. This study evaluated the relationship between RAI-131 and NSSPM in DTC survivors with long-term follow-up. MATERIALS AND METHODS Retrospective analysis of 413 DTC cases was performed; 252 received RAI-131 and 161 were treated with thyroidectomy alone. Exclusion criteria were: prior or synchronous non… CONTINUE READING
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