Is radiation dose reduction the right answer for HPV-positive head and neck cancer?

@article{Kimple2014IsRD,
  title={Is radiation dose reduction the right answer for HPV-positive head and neck cancer?},
  author={Randall J. Kimple and Paul M. Harari},
  journal={Oral oncology},
  year={2014},
  volume={50 6},
  pages={
          560-4
        }
}
Patients with head and neck squamous cell carcinoma (HNC) related to human papillomavirus (HPV) represent a growing and distinct patient cohort with unique molecular and epidemiologic characteristics. These patients have markedly improved survival outcomes compared to those with traditional HNC, leading some to advocate for treatment dose reduction. In this article, we review ongoing clinical trials investigating several ways to reduce therapeutic intensity for patients with HPV-positive HNC… CONTINUE READING
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Citations

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SHOWING 1-10 OF 17 CITATIONS

Human Papilloma Virus Associated Squamous Cell Carcinoma of the Head and Neck

  • Journal of sexually transmitted diseases
  • 2015
VIEW 3 EXCERPTS
CITES METHODS & BACKGROUND
HIGHLY INFLUENCED

HPV infection in oropharyngeal squamous cell carcinomas: correlation with tumor size.

  • Journal of B.U.ON. : official journal of the Balkan Union of Oncology
  • 2018
VIEW 1 EXCERPT
CITES BACKGROUND

G2-checkpoint targeting and radiosensitization of HPV/p16-positive HNSCC cells through the inhibition of Chk1 and Wee1.

  • Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
  • 2017
VIEW 1 EXCERPT
CITES BACKGROUND

Human papillomavirus and head and neck carcinomas: focus on evidence in the babel of published data

  • Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale
  • 2016

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