Is prostacyclin subserving a vasodilator effect of methoxamine involving alpha adrenoreceptors?


The influence of methoxamine on the contractile tension of isolated rat abdominal aorta, and on its capacity to produce a platelet antiaggregating substance, were explored. Methoxamine stimulated platelet antiaggregation and diminished arterial tone. The last action was blocked by phentolamine as well as by inhibitiors of cyclo-oxygenase and… (More)
DOI: 10.1007/BF01990425

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