Is perioperative plasma aprotinin concentration more predictable and constant after a weight-related dose regimen?


UNLABELLED To determine whether a weight-related dose had advantages over a fixed, large-dose regimen, we measured plasma concentrations of aprotinin by using an enzyme-linked immunosorbent assay method at set time points in 30 patients having heart surgery with cardiopulmonary bypass. A weight-related dose comprising a preincision bolus injection of 40,000… (More)


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