Is oxygen supply a limiting factor for survival during rewarming from profound hypothermia?

  title={Is oxygen supply a limiting factor for survival during rewarming from profound hypothermia?},
  author={Timofei V. Kondratiev and Kristina Flemming and Eivind S. P. Myhre and Mikhail A. Sovershaev and Torkjel Tveita},
  journal={American journal of physiology. Heart and circulatory physiology},
  volume={291 1},
It has been postulated that unsuccessful resuscitation of victims of accidental hypothermia is caused by insufficient tissue oxygenation. The aim of this study was to test whether inadequate O2 supply and/or malfunctioning O2 extraction occur during rewarming from deep/profound hypothermia of different duration. Three groups of rats (n = 7 each) were used: group 1 served as normothermic control for 5 h; groups 2 and 3 were core cooled to 15 degrees C, kept at 15 degrees C for 1 and 5 h… 

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