Is on-demand treatment effective in patients with severe haemophilia?

@article{Aznar2012IsOT,
  title={Is on-demand treatment effective in patients with severe haemophilia?},
  author={J A Aznar and Alfredo Ch{\'a}rlez Marco and Victor Jim{\'e}nez-Yuste and Elena Fern{\'a}ndez-Fontecha and Ruth Cecilia Vanegas P{\'e}rez and I Soto and Rafael Parra and Manuel Rey Moreno and Mar{\'i}a Eva Mingot and Andr{\'e}s Emilio Arcia Moret},
  journal={Haemophilia : the official journal of the World Federation of Hemophilia},
  year={2012},
  volume={18 5},
  pages={
          738-42
        }
}
On-demand therapy enables stopping haemorrhages rapidly, reducing joint pain and restoring joint mobility, but does not prevent the beginning and subsequent development of haemophilic arthropathy. The main objective of this study was to identify the clinical and orthopaedic status of severe haemophilic patients with bleeding phenotype receiving on-demand treatment in Spain. We conducted an epidemiological, observational, retrospective study, recruiting 167 patients from 36 centres (92% of them… CONTINUE READING
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