Is obesity an outcome of gonadotropin-releasing hormone agonist administration? Analysis of growth and body composition in 110 patients with central precocious puberty.

@article{Palmert1999IsOA,
  title={Is obesity an outcome of gonadotropin-releasing hormone agonist administration? Analysis of growth and body composition in 110 patients with central precocious puberty.},
  author={Mark R. Palmert and Maynard J. Mansfield and William Francis Crowley and John F. Crigler and J. Douglas Crawford and Paul A. Boepple},
  journal={The Journal of clinical endocrinology and metabolism},
  year={1999},
  volume={84 12},
  pages={
          4480-8
        }
}
Concern has been raised that children with central precocious puberty (CPP) are prone to the development of obesity. Here we report longitudinal height, weight, and body mass index (BMI) data from 96 girls and 14 boys with CPP before, during, and after GnRH agonist (GnRHa) administration. Skinfold thickness (n = 46) and percent body fat by dual energy x-ray absorptiometry (n = 21) were determined in subsets for more accurate assessment of body composition and to validate the use of the BMI SD… CONTINUE READING
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