Is obesity an inflammatory disease?

  title={Is obesity an inflammatory disease?},
  author={Eduardo J. B. Ramos and Yuan Xu and Irina V Romanova and Frank A. Middleton and Chung Chen and Robert J Quinn and Akio Inui and Undurti Das and Michael Marwan Meguid},
  volume={134 2},
BACKGROUND Most obese individuals have elevated concentrations of interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-alpha), markers of inflammation closely associated with diabetes, hypertension, and stroke. HYPOTHESIS Obesity is a low-grade inflammatory disease, and Roux-en-Y gastric bypass (RYGB) reduces biochemical markers of inflammation and modifies gene expression in hypothalamic food intake/energy-related nuclei and subcutaneous abdominal fat (SAF). METHODS Obesity was… CONTINUE READING
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