Is neuronal death required for seizure-induced epileptogenesis in the immature brain?

Abstract

Do seizures cause neuronal death? At least in the immature hippocampus, this may not be the critical question for determining the mechanisms of epileptogenesis. Neuronal injury and death have clearly been shown to occur in most epilepsy models in the mature brain, and are widely considered a prerequisite to seizure-induced epilepsy. In contrast, little… (More)

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@article{Baram2002IsND, title={Is neuronal death required for seizure-induced epileptogenesis in the immature brain?}, author={Tallie Z. Baram and Mariam Eghbal-Ahmadi and Roland A. Bender}, journal={Progress in brain research}, year={2002}, volume={135}, pages={365-75} }