Is multiple system atrophy with cerebellar ataxia (MSA-C) like spinocerebellar ataxia and multiple system atrophy with parkinsonism (MSA-P) like Parkinson’s disease? – A saccade study on pathophysiology

@article{Terao2016IsMS,
  title={Is multiple system atrophy with cerebellar ataxia (MSA-C) like spinocerebellar ataxia and multiple system atrophy with parkinsonism (MSA-P) like Parkinson’s disease? – A saccade study on pathophysiology},
  author={Yasuo Terao and Hideki Fukuda and Shinnichi Tokushige and Satomi Inomata-Terada and Yoshikazu Ugawa},
  journal={Clinical Neurophysiology},
  year={2016},
  volume={127},
  pages={1491-1502}
}
OBJECTIVE Patients with multiple system atrophy (MSA) are classified into those mainly manifesting cerebellar ataxia (MSA-C) and those mainly manifesting parkinsonism (MSA-P). Pathophysiological bases of these subtypes remain unclear. We hypothesized that MSA-C patients would resemble spinocerebellar degeneration patients and MSA-P patients would resemble Parkinson's disease (PD) patients in saccade abnormalities. METHODS We recorded visually guided and memory guided saccades (MGS) in 27 MSA… CONTINUE READING

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